BDBM375953 US10947243, Example 22::US9914735, Example 22

SMILES C[C@@H](Oc1cc(cc2nn(C)cc12)-c1ccc(cc1)N1CCOCC1)[C@H]1CNC(=O)C1

InChI Key InChIKey=QKPIWWMVTJIOSA-VQIMIIECSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 375953   

TargetTyrosine-protein kinase SYK [342-635](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375953(US10947243, Example 22 | US9914735, Example 22)
Affinity DataIC50:  12.8nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK [342-635](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375953(US10947243, Example 22 | US9914735, Example 22)
Affinity DataIC50:  12.8nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie—Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent